Association of higher axillary pathologic complete response rate with breast pathologic complete response after neoadjuvant chemotherapy.

ABSTRACT:

Background

To investigate the association of axillary pathologic complete response (pCR) rate among breast cancer patients with pCR after neoadjuvant chemotherapy (NCT).

Methods

The retrospective clinical data of 1,903 patients who were treated with NCT between March, 2010 and December, 2018, were collected from one Chinese database and analyzed. The correlations between clinicopathological characteristics and breast pCR with axillary pCR were calculated by χ² test. Binary logistic regression analysis was used for multivariate analysis. The relative risk of positive axillary nodes after NCT in patients with and without breast pCR was analyzed using a Cochran-Mantel-Haenszel (CMH) test stratified by initial N stage and tumor subtype.

Results

The rate of axil

SUBMITTER: Zhu J 

PROVIDER: S-EPMC7475504 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature