Determining the optimal puncture site of CT-guided transthoracic needle aspiration biopsy for the diagnosis of tuberculosis.

ABSTRACT:

Background

The purpose of this study was to determine the optimal puncture site of computed tomography (CT)-guided transthoracic needle aspiration biopsy for the diagnosis of tuberculosis (TB) by the comparison of clinical and radiological characteristics of TB patients stratified to different histopathological results.

Methods

We retrospectively analysed the data of clinically diagnosed TB patients with negative laboratory results between July 2016 and June 2018. Biopsy specimens were obtained from patients for Ziehl-Neelsen (Z-N) staining and TB-DNA.

Results

For the 356 TB patients, the positive rate of TB-DNA was 70.9%, which was significantly higher than that of Z-N staining (46.4%, P<0.001). The positive rate of lesions from upper lobe (76.4%, 155/203) was signif

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC7475607 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature