Incidence and preoperative predictors for major complications following radical nephroureterectomy.

ABSTRACT:

Background

Radical nephroureterectomy (RNU) is the referent standard for managing bulky, invasive, or high grade upper-tract urothelial carcinoma (UTUC). The UTUC patient population, however, generally harbor medical comorbidities thereby placing them at risk of surgical complications. This study reviews a large international cohort of RNU patients to define the risk of major complications and preoperative factors associated with their occurrence.

Methods

Patients undergoing RNU at 14 academic medical centers between 2002 and 2015 were retrospectively reviewed. Preoperative clinical, demographic, operative, and comorbidity indices were recorded. The modified Clavien-Dindo index was used to grade complications occurring within 30 days of surgery. The association between preop

SUBMITTER: Kocher NJ 

PROVIDER: S-EPMC7475660 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature