Measuring Treatment Response in Pediatric Trichotillomania: A Meta-Analysis of Clinical Trials.

ABSTRACT: Objectives: In clinical trials of pediatric trichotillomania (TTM), three instruments are typically employed to rate TTM severity: (1) the Massachusetts General Hospital Hair Pulling Scale (MGH-HPS), (2) the National Institute of Mental Health Trichotillomania Severity Scale (NIMH-TSS), and (3) the Trichotillomania Scale for Children (TSC). These instruments lack standardized definitions of treatment response, which lead researchers to determine their own definitions of response post hoc and potentially inflate results. We performed a meta-analysis to provide empirically determined accuracy measures for percentage reduction cut points in these three instruments. Methods: MEDLINE was searched for TTM clinical trials. A total of 67 studies were initially id

SUBMITTER: Farhat LC 

PROVIDER: S-EPMC7476376 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature