Validation of a Vision-Guided Mobility Assessment for <i>RPE65</i>-Associated Retinal Dystrophy.

ABSTRACT:

Purpose

To validate a vision-guided mobility assessment for individuals affected by RPE65-associated retinal dystrophy (RPE65-RD).

Methods

In this comparative cross-sectional study, 29 subjects, comprising 19 subjects with RPE65-RD and 10 normally-sighted subjects undertook three assessments of mobility: following a straight line, navigating a simple maze, and stepping over a sidewalk "kerb." Performance was quantified as the time taken to complete each assessment, number of errors made, walking speed, and percent preferred walking speed, for each assessment. Subjects also undertook assessments of visual acuity, contrast sensitivity, full-field static perimetry, and age-appropriate quality of life questionnaires. To identify the most relevant metric to q

SUBMITTER: Kumaran N 

PROVIDER: S-EPMC7476654 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature