Physical activity during and after breast cancer therapy and associations of baseline physical activity with changes in cardiac function by echocardiography.

ABSTRACT:

Background

Observational studies suggest that regular physical activity may reduce cardiovascular morbidity and cancer recurrence in survivors of breast cancer. The association between physical activity and cardiac function with breast cancer therapy is unknown.

Methods

Self-reported physical activity was assessed using the Godin Leisure-Time Exercise Questionnaire at repeated intervals in a longitudinal cohort study of 603 breast cancer participants treated with doxorubicin and/or trastuzumab. Multivariable regression models estimated associations between clinical variables and physical activity. Generalized estimating equations adjusted for prespecified variables estimated associations between baseline physical activity and longitudinal echocardiographic measures of systol

SUBMITTER: Upshaw JN 

PROVIDER: S-EPMC7476829 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature