Oral anticoagulation and clinical outcomes in COVID-19: An Italian multicenter experience.

ABSTRACT:

Background

Since the body of evidence addressing the coagulation derangements caused by Coronavirus disease (COVID-19) has been constantly growing, we investigated whether pre-hospitalization oral anticoagulation (OAC) or in-hospital heparin treatment could have a protective role among COVID-19 patients.

Method

In this cohort study, consecutive COVID-19 patients admitted to four different Italian Institutions were enrolled. Baseline demographic, clinical, laboratory, and radiological characteristics, as well as in-hospital treatment and outcomes were evaluated. The primary outcome was mortality.

Results

A total of 844 COVID-19 patients were enrolled as study cohort, n = 65 (7.7%) taking OACs prior to hospitalization. Regarding clinical outcomes, OAC patients developed

SUBMITTER: Schiavone M 

PROVIDER: S-EPMC7476907 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature