The cost-effectiveness of digital breast tomosynthesis in a population breast cancer screening program.

ABSTRACT:

Objectives

To evaluate at which sensitivity digital breast tomosynthesis (DBT) would become cost-effective compared to digital mammography (DM) in a population breast cancer screening program, given a constant estimate of specificity.

Methods

In a microsimulation model, the cost-effectiveness of biennial screening for women aged 50-75 was simulated for three scenarios: DBT for women with dense breasts and DM for women with fatty breasts (scenario 1), DBT for the whole population (scenario 2) or maintaining DM screening (reference). For DM, sensitivity was varied depending on breast density from 65 to 87%, and for DBT from 65 to 100%. The specificity was set at 96.5% for both DM and DBT. Direct medical costs were considered, including screening, biopsy and treatment costs. Sc

SUBMITTER: Wang J 

PROVIDER: S-EPMC7476964 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature