Type 1 and type 2 diabetes after gestational diabetes: a 23 year cohort study.

ABSTRACT:

Aims/hypothesis

The aim of this work was to examine the progression to type 1 and type 2 diabetes after gestational diabetes mellitus (GDM) in a 23 year follow-up study.

Methods

We carried out a cohort study of 391 women with GDM diagnosed by an OGTT or the use of insulin treatment during pregnancy, and 391 age- and parity-matched control participants, who delivered in 1984-1994 at the Oulu University Hospital, Finland. Diagnostic cut-off levels for glucose were as follows: fasting, ≥4.8 mmol/l; 1 h, ≥10.0 mmol/l; and 2 h, ≥8.7 mmol/l. Two follow-up questionnaires were sent (in 1995-1996 and 2012-2013) to assess the progression to type 1 and type 2 diabetes. Mean follow-up time was 23.1 (range 18.7-28.8) years.

Results

Type 1 diabetes developed (5.7%) during the first

SUBMITTER: Auvinen AM 

PROVIDER: S-EPMC7476985 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature