Predictive value of quantitative ¹⁸F-FDG-PET radiomics analysis in patients with head and neck squamous cell carcinoma.

ABSTRACT:

Background

Radiomics is aimed at image-based tumor phenotyping, enabling application within clinical-decision-support-systems to improve diagnostic accuracy and allow for personalized treatment. The purpose was to identify predictive 18-fluor-fluoro-2-deoxyglucose (¹⁸F-FDG) positron-emission tomography (PET) radiomic features to predict recurrence, distant metastasis, and overall survival in patients with head and neck squamous cell carcinoma treated with chemoradiotherapy.

Methods

Between 2012 and 2018, 103 retrospectively (training cohort) and 71 consecutively included patients (validation cohort) underwent ¹⁸F-FDG-PET/CT imaging. The 434 extracted radiomic features were subjected, after redundancy filtering, to a projection resulting in outcome-indep

SUBMITTER: Martens RM 

PROVIDER: S-EPMC7477048 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature