Ontology highlight
ABSTRACT:
SUBMITTER: Ye SB
PROVIDER: S-EPMC7477257 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Ye Shu-Biao SB Cheng Yi-Kan YK Zhang Lin L Zou Yi-Feng YF Chen Ping P Deng Yan-Hong YH Huang Yan Y Peng Jian-Hong JH Wu Xiao-Jian XJ Lan Ping P
NPJ precision oncology 20200907
Prior reports have indicated that defective mismatch repair (MMR) has a favorable impact on outcome in colorectal cancer patients treated with surgery, immunotherapy, or adjuvant chemotherapy. However, the impact of MMR status on response to neoadjuvant radiotherapy in rectal cancer is not well understood. Here we report that dMMR was associated with improved disease-free survival (DFS) (<i>P</i> = 0.034) in patients receiving neoadjuvant chemotherapy (NCT). Patients with dMMR tumors who receive ...[more]