Ontology highlight
ABSTRACT:
SUBMITTER: Gupta A
PROVIDER: S-EPMC7477354 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Gupta Ayam A Shukla Nidhi N Nehra Mamta M Gupta Sonal S Malik Babita B Mishra Ashwani Kumar AK Vijay Maneesh M Batra Jyotsna J Lohiya Nirmal Kumar NK Sharma Devendra D Suravajhala Prashanth P
Frontiers in genetics 20200825
Prostate cancer (PCa) is the third most common cancer among men in India, and no next-generation sequencing (NGS) studies have been attempted earlier. Recent advances in NGS have heralded the discovery of biomarkers from Caucasian/European and Chinese ancestry, but not much is known about the Indian phenotype/variant of PCa. In a pilot study using the whole exome sequencing of benign/PCa patients, we identified characteristic mutations specific to the Indian sub-population. We observed a large n ...[more]