Simulating transmission of ESKAPE pathogens plus C. difficile in relevant clinical scenarios.

ABSTRACT:

Background

The prevalence of healthcare-acquired infections (HAI) and rising levels of antimicrobial resistance places significant economic and public health burdens on modern healthcare systems. A group of highly drug resistant pathogens known as the ESKAPE pathogens, along with C. difficile, are the leading causes of HAIs. Interactions between patients, healthcare workers, and environmental conditions impact disease transmission. Studying pathogen transfer under varying contact scenarios in a controlled manner is critical for understanding transmission and disinfectant strategies. In lieu of human subject research, this method has the potential to contribute to modeling the routes of pathogen transmission in healthcare settings.

Methods

To overcome these challenges, we hav

SUBMITTER: Weber KL 

PROVIDER: S-EPMC7477864 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature