Osprey: Open-source processing, reconstruction & estimation of magnetic resonance spectroscopy data.

ABSTRACT:

Background

Processing and quantitative analysis of magnetic resonance spectroscopy (MRS) data are far from standardized and require interfacing with third-party software. Here, we present Osprey, a fully integrated open-source data analysis pipeline for MRS data, with seamless integration of pre-processing, linear-combination modelling, quantification, and data visualization.

New method

Osprey loads multiple common MRS data formats, performs phased-array coil combination, frequency-and phase-correction of individual transients, signal averaging and Fourier transformation. Linear combination modelling of the processed spectrum is carried out using simulated basis sets and a spline baseline. The MRS voxel is coregistered to an anatomical image, which is segmented for tissue co

SUBMITTER: Oeltzschner G 

PROVIDER: S-EPMC7477913 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature