Selective enhancement of low-gamma activity by tACS improves phonemic processing and reading accuracy in dyslexia.

ABSTRACT: The phonological deficit in dyslexia is associated with altered low-gamma oscillatory function in left auditory cortex, but a causal relationship between oscillatory function and phonemic processing has never been established. After confirming a deficit at 30 Hz with electroencephalography (EEG), we applied 20 minutes of transcranial alternating current stimulation (tACS) to transiently restore this activity in adults with dyslexia. The intervention significantly improved phonological processing and reading accuracy as measured immediately after tACS. The effect occurred selectively for a 30-Hz stimulation in the dyslexia group. Importantly, we observed that the focal intervention over the left auditory cortex also decreased 30-Hz activity in the right superior temporal cortex, resulting i

SUBMITTER: Marchesotti S 

PROVIDER: S-EPMC7478834 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature