The Profiling of DNA Methylation and Its Regulation on Divergent Tenderness in Angus Beef Cattle.

ABSTRACT: Beef is an essential food source in the world. Beef quality, especially tenderness, has a significant impact on consumer satisfaction and industry profit. Many types of research to date have focused on the exploration of physiological and developmental mechanisms of beef tenderness. Still, the role and impact of DNA methylation status on beef tenderness have yet to be elucidated. In this study, we exhaustively analyzed the DNA methylation status in divergent tenderness observed in Angus beef. We characterized the methylation profiles related to beef tenderness and explored methylation distributions on the whole genome. As a result, differentially methylated regions (DMRs) associated with tenderness and toughness of beef were identified. Importantly, we annotated these DMRs on the bovine ge

SUBMITTER: Zhao C 

PROVIDER: S-EPMC7479246 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature