Still No Substantial Evidence to Use Prophylactic Antibiotic at Operative Vaginal Delivery: Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Postpartum maternal infection is still a common problem worldwide, mainly due to obstetric risk factors. The use of prophylactic antibiotic at operative vaginal delivery (OVD), taking it as a standalone risk factor, has been controversial. The purpose of this review was to rigorously evaluate the association of OVD with postpartum infection and shed light on such highly controversial issue.

Methods

A computer-based literature search was done mainly in the databases of PUBMED, HINARI health research, and the Cochrane library. Systematic review and meta-analysis were done by including 14 articles published between 1990 and August 2019.

Results

The average absolute risk of postpartum infection at OVD from seven large cohort studies was 1%. Few studies showed a

SUBMITTER: Berhan Y 

PROVIDER: S-EPMC7479451 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature