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The Predictive Value of Serum Uric Acid on Acute Kidney Injury following Traumatic Brain Injury.


ABSTRACT:

Backgrounds

Acute kidney injury (AKI) is a prevalent nonneurological complication in patients with traumatic brain injury (TBI). We designed this study to explore the association between serum uric acid (SUA) level and the occurrence of AKI following TBI.

Methods

This is a retrospective single-center study. A total of 479 patients admitted with TBI were included in this study. We utilized SUA and other risk factors for AKI to construct a predictive model by performing multivariate logistic regression. 374 patients and 105 patients were, respectively, divided into a training set and validation set. The predictive value of the single SUA and constructed model was evaluated by drawing a receiver operating characteristic (ROC) curve. AKI was diagnosed according to the KIDGO crit

SUBMITTER: Wang RR 

PROVIDER: S-EPMC7479452 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature