Changes in Blood Pressure and Arterial Hemodynamics following Living Kidney Donation.

ABSTRACT:

Background and objectives

The Effect of a Reduction in GFR after Nephrectomy on Arterial Stiffness and Central Hemodynamics (EARNEST) study was a multicenter, prospective, controlled study designed to investigate the associations of an isolated reduction in kidney function on BP and arterial hemodynamics.

Design, setting, participants, & measurements

Prospective living kidney donors and healthy controls who fulfilled criteria for donation were recruited from centers with expertise in vascular research. Participants underwent office and ambulatory BP measurement, assessment of arterial stiffness, and biochemical tests at baseline and 12 months.

Results

A total of 469 participants were recruited, and 306 (168 donors and 138 controls) were followed up at 12 months. In th

SUBMITTER: Price AM 

PROVIDER: S-EPMC7480552 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature