Postmenstrual age at discharge in premature infants with and without ventilatory pattern instability.

ABSTRACT:

Rationale

To determine if ventilatory pattern instability, manifested as periodic breathing (PB) during physiologic challenge testing, affects postmenstrual age (PMA) at discharge.

Methods

Eighty infants underwent challenge testing at 36 weeks PMA. Infants breathing supplemental O₂ received a room air challenge (RAC, N = 51); those breathing ambient air underwent a hypoxic challenge test (HCT, N = 29). Infants were assigned one of four ventilatory control phenotypes based on the presence or absence of PB during their test, and if they passed or failed because of hypoxemia during the challenge test.

Results

There were no clinical or demographic differences between groups. Infants who passed their challenge testing were, on average, discharged 1.6 weeks soone

SUBMITTER: Hoover J 

PROVIDER: S-EPMC7480785 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature