Co-seasonality and co-detection of respiratory viruses and bacteraemia in children: a retrospective analysis.

ABSTRACT:

Objectives

The aim of this study was to assess the co-seasonality and co-detection of respiratory viral infections and bacteraemia in children since the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13).

Methods

Children <18 years old were eligible for inclusion if they had a respiratory infection and a positive PCR-based assay for respiratory viruses as well as a positive blood culture between 2010 and 2018 at a single referral centre in the United States, regardless of their underlying medical condition or antibiotic treatment history. Monthly incidence rates of respiratory viruses and bacteraemia were analysed with a seasonal-trend decomposition procedure based on loess (STL) and cross-correlation functions using time series regression modelling.

Res

SUBMITTER: Choe YJ 

PROVIDER: S-EPMC7481115 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature