Hyperprolactinemia in end-stage renal disease and effects of frequent hemodialysis.

ABSTRACT:

Introduction

End-stage renal disease is associated with elevations in circulating prolactin concentrations, but the association of prolactin concentrations with intermediate health outcomes and the effects of hemodialysis frequency on changes in serum prolactin have not been examined.

Methods

The FHN Daily and Nocturnal Dialysis Trials compared the effects of conventional thrice weekly hemodialysis with in-center daily hemodialysis (6 days/week) and nocturnal home hemodialysis (6 nights/week) over 12 months and obtained measures of health-related quality of life, self-reported physical function, mental health and cognition. Serum prolactin concentrations were measured at baseline and 12-month follow-up in 70% of the FHN Trial cohort to examine the associations among serum pr

SUBMITTER: Lo JC 

PROVIDER: S-EPMC7481141 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature