Distinct serum metabolomic signatures of multiparous and primiparous dairy cows switched from a moderate to high-grain diet during early lactation.

ABSTRACT:

Introduction

Feeding of high-grain diets is common in cows during early lactation, but increases the odds of metabolic derailments, which can likely be detected as undesirable shifts in the serum metabolome signature.

Objectives

The present study aimed to identify the metabolic signatures of the serum metabolome of early lactation dairy cows switched from a moderate to a high-grain diet.

Methods

Targeted ESI-LC-MS/MS-based metabolomics was used to characterize metabolic alterations in the serum of early lactation multiparous (MP, n = 16) and primiparous (PP, n = 8) Simmental cows, according to parity and feeding phase. Data were analysed using different data mining approaches.

Results

Carnitine, acetylcarnitine, propionoylcarnitine, amino acid related compounds

SUBMITTER: Pacifico C 

PROVIDER: S-EPMC7481167 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature