Effect of Parkinson's disease and two therapeutic interventions on muscle activity during walking: a systematic review.

ABSTRACT: Gait deficits are a common feature of Parkinson's disease (PD) and predictors of future motor and cognitive impairment. Understanding how muscle activity contributes to gait impairment and effects of therapeutic interventions on motor behaviour is crucial for identifying potential biomarkers and developing rehabilitation strategies. This article reviews sixteen studies that investigate the electromyographic (EMG) activity of lower limb muscles in people with PD during walking and reports on their quality. The weight of evidence establishing differences in motor activity between people with PD and healthy older adults (HOAs) is considered. Additionally, the effect of dopaminergic medication and deep brain stimulation (DBS) on modifying motor activity is assessed. Results indicated greater p

SUBMITTER: Islam A 

PROVIDER: S-EPMC7481232 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature