Pulmonary oligometastases treated by stereotactic body radiation therapy (SBRT): a single institution's experience.

ABSTRACT:

Background

To investigate the effect of stereotactic body radiation therapy (SBRT) on pulmonary oligometastases and to analyze the clinical factors and dose parameters affecting local recurrence-free survival (LRFS) and overall survival (OS).

Methods

This study retrospectively enrolled a total of 84 patients (148 lesions) treated in our department from May 2015 to November 2018. Pulmonary oligometastases was defined as up to 5 metastatic lesions in the lung and with both the primary tumor and any extra-thoracic metastases being controlled. Patients receiving a BED₁₀ (biological effective dose, α/β =10) of SBRT ≥75 Gy and a dose/fraction ≥4 Gy were enrolled. The patient group consisted of 52 men (61.9%) and 32 women (38.1%), with a median age 56 years (range, 29-80

SUBMITTER: Chai G 

PROVIDER: S-EPMC7481615 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature