Impact of time-to-treatment on overall survival of non-small cell lung cancer patients-an analysis of the national cancer database.

ABSTRACT:

Background

The association between time-to-treatment and outcomes for lung cancer has not been conclusively established. In this study, we evaluated the effect of time-to-treatment on the overall 5-year survival of patients with non-small cell lung cancer (NSCLC) with cancer stage at diagnosis.

Methods

We analyzed data in the National Cancer Data Base for adult patients newly diagnosed with NSCLC in 2003-2011 (N=693,554). Extended Cox regression with counting process was used to model the effect of time-to-treatment on survival, adjusted for demographic and clinical factors. Multivariable analyses were performed separately for the groups with different stages at diagnosis. Time-to-treatment was defined as the interval between diagnosis and treatment initiation, with the cate

SUBMITTER: Anggondowati T 

PROVIDER: S-EPMC7481622 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature