Radiomic features of primary tumor by lung cancer stage: analysis in BRAF mutated non-small cell lung cancer.

ABSTRACT:

Background

The clinical features and traditional semantic imaging characteristics of BRAF-mutated non-small cell lung cancer (NSCLC) have been previously reported. The radiomic features of BRAF-mutated NSCLC and their role in predicting cancer stage, however, have yet to be investigated. This study's goal is to assess the differences in CT radiomic features of primary NSCLC driven by BRAF mutation and stratified by tumor-node-metastasis (TNM) staging.

Methods

Our IRB approved study included 62 patients with BRAF mutations (V600 in 27 and non-V600 in 35 patients), who underwent contrast-enhanced chest CT. Tumor stage was determined based on the 8^th edition of TNM staging. Two thoracic radiologists assessed the primary tumor imaging featu

SUBMITTER: Padole A 

PROVIDER: S-EPMC7481629 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature