¹⁸F-RGD PET/CT imaging reveals characteristics of angiogenesis in non-small cell lung cancer.

ABSTRACT:

Background

The objective of this study was to explore the benefit of ¹⁸F-AlF-NOTA-PRGD2 positron emission tomography/computed tomography (denoted as ¹⁸F-RGD PET/CT) imaging for determining the clinical pathologic features of non-small cell lung cancer (NSCLC).

Methods

Seventy-two patients with NSCLC (37 cases of adenocarcinoma and 35 cases of squamous carcinoma) were enrolled to receive ¹⁸F-RGD PET/CT scanning pretreatment. The peak standard uptake value (SUV_peak), mean standard uptake value (SUV_mean), angiogenic tumor volume (ATV) and total lesion angiogenesis (TLA) of tumors were determined using an automated contouring program. Cases were classified according to the tumor, lymph node, metastasis (TNM) stage.

Result

SUBMITTER: Li L 

PROVIDER: S-EPMC7481644 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature