Influence of Oxidation Degree of Graphene Oxide on Its Nuclear Relaxivity and Contrast in MRI.

ABSTRACT: Graphene oxide (GO) serves as a versatile platform for various applications, with the oxygen content of GO playing an important role in governing its properties. In the present study, different GO types covering a wide range of oxidation degree were prepared using our newly developed two-step method involving ball milling of graphite followed by its oxidation to GO. In addition to the variations in their physicochemical properties, the different GO types exhibited differences in proton relaxivity due to their paramagnetic nature. Nuclear magnetic resonance spectroscopy studies showed that the degree of oxidation of GO perturbs its nuclear relaxation properties and, together with intercalated Mn²⁺ ions, provides large contrast variation in magnetic resonance imaging (MRI). The st

SUBMITTER: Mohanta Z 

PROVIDER: S-EPMC7482091 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature