Transient receptor potential channels: current perspectives on evolution, structure, function and nomenclature.

ABSTRACT: The transient receptor potential superfamily of ion channels (TRP channels) is widely recognized for the roles its members play in sensory nervous systems. However, the incredible diversity within the TRP superfamily, and the wide range of sensory capacities found therein, has also allowed TRP channels to function beyond sensing an organism's external environment, and TRP channels have thus become broadly critical to (at least) animal life. TRP channels were originally discovered in Drosophila and have since been broadly studied in animals; however, thanks to a boom in genomic and transcriptomic data, we now know that TRP channels are present in the genomes of a variety of creatures, including green algae, fungi, choanoflagellates and a number of other eukaryotes. As a result, the o

SUBMITTER: Himmel NJ 

PROVIDER: S-EPMC7482286 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature