Data sharing: experience of accessing individual patient data from completed randomised controlled trials in vascular and cognitive medicine.

ABSTRACT:

Objectives

Meta-analysis based on individual patient data (IPD) from randomised trials is superior to using published summary data since it facilitates subgroup and multiple variable analyses. Guidelines and funders expect that researchers share IPD for bona fide analyses, but in practice, this is done variably. Here, we report the experience of obtaining IPD for two collaborative analysis studies.

Setting

Two linked studies required IPD from published randomised trials. The leading researchers for eligible trials were approached and asked to share IPD including trial characteristics, patient demographics, baseline clinical data and outcome measures.

Participants

Participants in eligible randomised controlled trials included patients with or at risk of cognitive decli

SUBMITTER: Scutt P 

PROVIDER: S-EPMC7482449 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature