Investigating persistent measles dynamics in Niger and associations with rainfall.

ABSTRACT: Measles is a major cause of child mortality in sub-Saharan Africa. Current immunization strategies achieve low coverage in areas where transmission drivers differ substantially from those in high-income countries. A better understanding of measles transmission in areas with measles persistence will increase vaccination coverage and reduce ongoing transmission. We analysed weekly reported measles cases at the district level in Niger from 1995 to 2004 to identify underlying transmission mechanisms. We identified dominant periodicities and the associated spatial clustering patterns. We also investigated associations between reported measles cases and environmental drivers associated with human activities, particularly rainfall. The annual and 2-3-year periodicities dominated the reporting dat

SUBMITTER: Blake A 

PROVIDER: S-EPMC7482562 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature