Structure-based Hamiltonian model for IsiA uncovers a highly robust pigment-protein complex.

ABSTRACT: The iron stress-induced protein A (IsiA) is a source of interest and debate in biological research. The IsiA supercomplex, binding over 200 chlorophylls, assembles in multimeric rings around photosystem I (PSI). Recently, the IsiA-PSI structure from Synechocystis sp. PCC 6803 was resolved to 3.48 Å. Based on this structure, we created a model simulating a single excitation event in an IsiA monomer. This model enabled us to calculate the fluorescence and the localization of the excitation in the IsiA structure. To further examine this system, noise was introduced to the model in two forms-thermal and positional. Introducing noise highlights the functional differences in the system between cryogenic temperatures and biologically relevant temperatures. Our results show that the energet

SUBMITTER: Schoffman H 

PROVIDER: S-EPMC7482578 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature