Preoperative outpatient blood pressure variability predicts postoperative mortality, readmission and morbidity after surgery.

ABSTRACT:

Background

Outpatient blood pressure variability (BPV) predicts hospitalization and death in non-surgical patients independently of hypertension. We hypothesized that preoperative BPV predicts postoperative outcomes.

Methods

We assessed 22,233 veterans undergoing CABG, colectomy, hip replacement, pancreatectomy, carotid endarterectomy or AV-fistula with ≥10 outpatient BP's over three preoperative years. Calculating BPV as SD of systolic or diastolic BP, we used logistic regression considering demographics, comorbidities, and pre-admission cardiovascular medications to estimate odds ratios for 90-day mortality or readmission, MI, CVA, renal failure, and wound infection, choosing the lowest 5%ile of systolic/diastolic BPV for reference.

Results

Covariate-adjusted ORs fo

SUBMITTER: Basson MD 

PROVIDER: S-EPMC7483253 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature