Time trends of delirium rates in the intensive care unit.

ABSTRACT:

Background

Effects of clinical practice changes on ICU delirium are not well understood.

Objectives

Determine ICU delirium rates over time.

Methods

Data from a previously described screening cohort of the Pharmacological Management of Delirium trial was analyzed. Richmond Agitation-Sedation Scale (RASS) and Confusion Assessment Method for the ICU (CAM-ICU) were assessed twice daily. We defined: Any delirium (positive CAM-ICU at any time during ICU stay) and ICU-acquired delirium (1st CAM-ICU negative with a subsequent positive CAM-ICU). Mixed-effects logistic regression models were used to test for differences.

Results

2742 patient admissions were included. Delirium occurred in 16.5%, any delirium decreased [22.7% to 10.2% (p < 0.01)], and ICU-acquired delirium

SUBMITTER: Khan SH 

PROVIDER: S-EPMC7483280 | biostudies-literature | 2020 Sep - Oct

REPOSITORIES: biostudies-literature