The Clinical Research Landscape of Pediatric Drug-Resistant Epilepsy.

ABSTRACT:

Objective

To characterize the clinical research landscape of pediatric drug-resistant epilepsy (DRE) with a focus on neurotechnology.

Method

We searched the ClinicalTrials.gov registry using the terms "epilepsy" and "drug resistant" for studies including participants age 0-17 years. Returns were grouped by intervention (eg, neurotechnological, drug). Key trial features such as age range, trial status and outcomes were compared across interventions.

Results

We identified 101 registered trials with pediatric DRE patients. Thirty-two (32%) investigate neurotechnological interventions, devices, or diagnostic procedures; 13 (41%) are currently active. Among neurotechnology trials, 15 (46%) investigate vagus nerve stimulation, transcranial direct current stimulation, or dee

SUBMITTER: Kaal KJ 

PROVIDER: S-EPMC7483355 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature