HIV incidence in US first-time blood donors and transfusion risk with a 12-month deferral for men who have sex with men.

ABSTRACT: In 2015, the US Food and Drug Administration published revised guidance that recommended a change in blood donor deferral of men who have sex with men (MSM) from an indefinite to a 12-month deferral since the donor last had sex with a man. We assessed whether HIV incidence in first-time blood donors or associated transfusion risk increased. Donations in 4 major blood collection organizations were monitored for 15 months before and 2 years after implementation of the 12-month MSM deferral policy. HIV-positive donations were classified as recently acquired or long-term using a recent infection testing algorithm and incidence in both periods estimated. Residual transfusion transmission risk was estimated by multiplying incidence by the length of the infectious window period. The latter was es

SUBMITTER: Grebe E 

PROVIDER: S-EPMC7483431 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature