Impact of Deceased Donor Management on Donor Heart Use and Recipient Graft Survival.

ABSTRACT:

Background

Current risk-adjusted models used to predict donor heart use and cardiac graft survival from organ donors after brain death (DBDs) do not include bedside critical care data. We sought to identify novel independent predictors of heart use and graft survival to better understand the relationship between donor management and transplantation outcomes.

Study design

We conducted a prospective observational study of DBDs managed from 2008 to 2013 by 10 organ procurement organizations. Demographic data, critical care parameters, and treatments were recorded at 3 standardized time points during donor management. The primary outcomes measures were donor heart use and cardiac graft survival.

Results

From 3,433 DBDs, 1,134 hearts (33%) were transplanted and 969 cardiac

SUBMITTER: Swanson EA 

PROVIDER: S-EPMC7483537 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature