The Microbiome-Metabolome Response in the Colon of Piglets Under the Status of Weaning Stress.

ABSTRACT: Weaning is stressful for piglets involving nutritional, physiological, and psychological challenges, leading to an increase in the secretion of cortisol, changes in gut microbiome and metabolites, whereas the underlying relationships remain unclear. To elucidate this, 14 Meishan female piglets were divided into the weaning group and the suckling group at the age of 21 days paired by litter and body weight. After 48 h of experiment, weaned piglets had lower body weight, but higher salivary cortisol level than that of their suckling litter mates (P < 0.05). The composition of the colonic bacterial community and metabolites were different between the two groups, and the first predominant genus of the suckling and weaned piglets colonic microbiome were Bacteroides and Prevotel

SUBMITTER: Jiang X 

PROVIDER: S-EPMC7483555 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature