Surgical Management of the Axilla in Elderly Women With Node-Positive Breast Cancer.

ABSTRACT:

Background

Elderly women with clinically node-positive (cN+) breast cancer (BC) often have comorbidities that limit life expectancy and complicate treatment. We sought to determine whether the number of lymph nodes (LNs) retrieved among older women with node-positive BC was associated with overall survival (OS).

Methods

Using the National Cancer Database (2010-2015), women 70-90 y with cN + BC and ≥1 LNs removed were categorized by treatment sequence: upfront surgery or neoadjuvant chemotherapy (NAC). Multivariable Cox proportional hazards models with restricted cubic splines characterized the functional association of LN retrieval with OS; threshold values of LN retrieval were estimated. Cox proportional hazards models were used to estimate the association of LN retrieval g

SUBMITTER: Marks CE 

PROVIDER: S-EPMC7483590 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature