Amygdala Functional Connectivity Features in Grief: A Pilot Longitudinal Study.

ABSTRACT:

Objective

Acute grief, in an important minority of older adults, can become protracted, intense, and debilitating, leading to the development of complicated grief (CG). However, the neurobiologic mechanisms underlying a maladaptive grief response after an attachment loss are unknown. The current study aimed to examine the amygdala brain network features that cross-sectionally explain the symptom variance and longitudinally relate to grief symptom trajectories after an attachment loss.

Methods

Baseline amygdala functional connectivity (Fc) was assessed using a seed-based resting-state functional magnetic resonance imaging method in 35 adults who were within 1-year after death of a loved one and 21 healthy comparison (HC) participants. Magnetic resonance imaging scans were obt

SUBMITTER: Chen G 

PROVIDER: S-EPMC7483593 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature