Integrative Review of Gut Microbiota and Expression of Symptoms Associated With Neonatal Abstinence Syndrome.

ABSTRACT:

Background

Neonatal exposure and subsequent withdrawal from maternal substance use disorder are a growing problem and consequence of the current opioid epidemic. Neonatal abstinence syndrome (NAS) is defined by a specified cluster of symptoms with treatment guided by the expression and severity of these symptoms. The mechanisms or pathophysiology contributing to the development of NAS symptoms are not well known, but one factor that may influence NAS symptoms is the gut microbiota.

Objectives

The purpose of this integrative review was to examine evidence that might show if and how the gut microbiota influence expression and severity of symptoms similar to those seen in NAS.

Methods

Using published guidelines, a review of research studies that focused on the gut microb

SUBMITTER: Sealschott SD 

PROVIDER: S-EPMC7483611 | biostudies-literature | 2020 Sep/Oct

REPOSITORIES: biostudies-literature