Returning genomic results in a Federally Qualified Health Center: the intersection of precision medicine and social determinants of health.

ABSTRACT:

Purpose

This report describes the return of sequencing results to low-income Latino participants recruited through a Federally Qualified Health Center (FQHC). We describe challenges in returning research results secondary to social determinants of health and present lessons learned to guide future genomic medicine implementation studies in low-resource settings.

Methods

Five hundred Latino adults (76% women) consented to research sequencing for a predetermined panel of actionable genes. Providers and staff from the FQHC were engaged to align processes with the practice and a community advisory board grounded the project in the local community.

Results

A pathogenic/likely pathogenic variant was present in 10 participants (2%). Challenges in return of results included t

SUBMITTER: Shaibi GQ 

PROVIDER: S-EPMC7483616 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature