Cesarean delivery and the risk of allergic rhinitis in children.

ABSTRACT:

Background

Cesarean delivery (C-section) may influence the infant microbiome and affect immune system development and subsequent risk for allergic rhinitis (AR).

Objective

To investigate the association between C-section and AR at ages 6, 8, and 10 years.

Methods

Data were collected prospectively through Kaiser Permanente Northern Californias (KPNC) integrated healthcare system. Children were eligible if they were born in a KPNC hospital and remained in the KPNC system for minimum 6 years (n = 117,768 age 6; n = 75,115 age 8; n = 40,332 age 10). Risk ratios (RR) for C-section and AR were estimated at each follow-up age and adjusted for important covariates, including intrapartum antibiotics, pre-pregnancy body mass index, maternal allergic morbidities, and breastfeedi

SUBMITTER: Richards M 

PROVIDER: S-EPMC7483751 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature