First report of equine parvovirus-hepatitis-associated Theiler's disease in Europe.

ABSTRACT:

Background

Equine parvovirus-hepatitis (EqPV-H) has been proposed as the aetiological cause of Theiler's disease, also known as serum hepatitis. EqPV-H-associated Theiler's disease has not been previously reported in Europe.

Objectives

To determine whether EqPV-H infection was associated with a 2018-2019 outbreak of Theiler's disease in four horses on a studfarm.

Study design

Descriptive case series.

Methods

The medical records of four horses from the same farm diagnosed with fatal Theiler's disease were examined retrospectively. Information collected included a clinical history, physical examination findings, tetanus antitoxin exposure, serum biochemistry and necropsy reports. Liver tissue from all four horses was tested for EqPV-H using PCR and in situ hybrid

SUBMITTER: Vengust M 

PROVIDER: S-EPMC7483838 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature