Parietal Cortex Is Required for the Integration of Acoustic Evidence.

ABSTRACT: Sensory-driven decisions are formed by accumulating information over time. Although parietal cortex activity is thought to represent accumulated evidence for sensory-based decisions, recent perturbation studies in rodents and non-human primates have challenged the hypothesis that these representations actually influence behavior. Here, we asked whether the parietal cortex integrates acoustic features from auditory cortical inputs during a perceptual decision-making task. If so, we predicted that selective inactivation of this projection should impair subjects' ability to accumulate sensory evidence. We trained gerbils to perform an auditory discrimination task and obtained measures of integration time as a readout of evidence accumulation capability. Minimum integration time was calculated

SUBMITTER: Yao JD 

PROVIDER: S-EPMC7483995 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature