Early adaptive thermogenesis is a determinant of weight loss after six weeks of caloric restriction in overweight subjects.

ABSTRACT:

Background

Adaptive thermogenesis during prolonged energy deficit refers to the greater than expected reduction in energy expenditure (EE) independent of concomitant loss of metabolically active body mass.

Objective

As inter-individual variability in the magnitude of adaptive thermogenesis may influence the extent of energy deficit thereby predicting the amount of weight reduction, we investigated whether early adaptive thermogenesis is a determinant of weight loss after 6 weeks of daily 50% caloric restriction in an inpatient setting.

Design and methods

The current study reports the results of an exploratory, secondary analysis in overweight but otherwise healthy subjects (n = 11, 7 men, 35 ± 9y, BMI = 40 ± 7 kg/m², body fat = 63.3 ± 5.3%). Body compositio

SUBMITTER: Heinitz S 

PROVIDER: S-EPMC7484122 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature