Neoepitopes as Difference Makers for General Cancer Vaccines?

ABSTRACT: The cancer mutanome has been associated with disease prognosis as well as response to interventional immunotherapy and provides a substrate for development of personalized vaccines targeting tumor neoepitopes. Recent findings suggest that neoantigen-based vaccines may represent general interventional approaches for patients with solid cancers, regardless of their inherent mutational burden.See related article by Fang et al., p. 4511.

SUBMITTER: Filderman JN 

PROVIDER: S-EPMC7484287 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature