Medical regimens for abortion at 12 weeks and above: a systematic review and meta-analysis.

ABSTRACT:

Background

Mifepristone and misoprostol are recommended for second-trimester medical abortion, but consensus is unclear on the ideal regimen.

Objectives

The objectives were to systematically review randomized controlled trials (RCTs) investigating efficacy, safety and satisfaction of medical abortion at ≥ 12 weeks' gestation.

Data sources

We searched PubMed, Popline, Embase, Global Index Medicus, Cochrane Controlled Register of Trials and International Clinical Trials Registry Platform from January 2008 to May 2017.

Study eligibility participants and interventions

We included RCTs on medical abortion at ≥ 12 weeks' gestation using mifepristone and/or misoprostol. We excluded studies with spontaneous abortion, fetal demise and mechanical cervical ripening and th

SUBMITTER: Whitehouse K 

PROVIDER: S-EPMC7484538 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature