Development and characterization of functionalized glyco thiolate capped gold nanoparticles for biological applications.

ABSTRACT: Glyco-gold nanoparticles (AuNPs) in aqueous dispersions were prepared by two approaches, namely direct reduction and ligand substitution methods. In the direct method, potassium salts of glyco thiols, with the general formula (C₆H₁₁O₆)NH(CH₂) _n CH₂SK (where L1, n = 1; L2, n = 2; L3, n = 3, L4, n = 4; L5, n = 5), were used as reducing and capping agents to give the glyco thiolate capped gold nanoparticles (AuNPs G1-G5); meanwhile in the ligand exchange experiments, L1-L5 and their acetylated forms (L6-L8) replaced citrate ions in citrate-capped gold nanoparticles to give additional AuNPs G6-G11.

SUBMITTER: Adokoh CK 

PROVIDER: S-EPMC7485141 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature